Mononucleosis tests is a blood test to detect antibodies against Epstein-Barr virus (EBV). Test cassette suitable for whole blood, serum or plasma, with buffer and pipette. Separate lancets are also available. Mononucleosis (also called mono) is an illness caused by EBV. Once formed, EBV antibodies usually remain in a person’s blood for life. Mono most often affects young people between the ages of 15 and 24. Epstein-Barr virus (EBV) can be found in saliva and mucus (from the nose and throat) and sometimes in tears.